Ruling on using honey to cleanse and purify the eyes; is that regarded as changing the creation of Allah?

There is nothing wrong with using permissible things, such as
natural herbs and foods like eggs, yoghurt, honey and so on, for cosmetic
purposes, to cleanse the skin, remove dark spots, and the like. 

That is not regarded as changing the creation of Allah,
because the kind of change that is blameworthy is that which is permanent. 

See the answers to questions no. 161935
and 174371 

Using honey for the purpose of cleansng the eyes, and to make
the white of the eyes whiter and the brown of the eyes lighter, does not
come under the heading of changing the creation of Allah, because it does
not change the appearance or colour of the eye. The white will still be
white, and the black will still be black, except that there is nothing wrong
with using honey to cleanse the place, make the colours clearer, and remove
dirt. 

At-Tirmidhi (1757) narrated from Ibn ‘Abbaas that the Prophet
(blessings and peace of Allah be upon him) said: “Apply antimony to your
eyes, for it makes the vision clear and makes the hair  grow.” Classed as
saheeh by al-Albaani in Saheeh at-Tirmidhi. 

Al-Mubaarakfoori said in Tuhfat al-Ahwadhi: That is,
it improves the vision and cleanses the eye. End quote. 

At-Tabaraani narrated in al-Kabeer (183), from ‘Ali
ibn Abi Taalib (may Allah be pleased with him), that the Messenger of Allah
(blessings and peace of Allah be upon him) said: “You should use antimony,
because it makes the hair grow, removes dirt, and makes the vision clear.”
Classed as hasan by al-Albaani in as-Saheehah (665).

Ibn al-Qayyim (may Allah have mercy on him) said: 

Kohl is good for the eye, improves and clears the vision,
cleanses it of impurities, and may also be a kind of adornment.

End quote. 

Zaad al-Ma‘aad
(4/259) 

Making the vision clear, cleansing the eye and removing dirt
do not come under the heading of changing the creation of Allah. 

And Allah knows best.